NEUTRALIZING ANTIBODIES TO EBOLA VIRUS GLYCOPROTEIN AND THEIR USE

Neutralizing antibodies and antigen binding fragments that specifically bind to Ebola virus glycoprotein are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. Methods for detecting Ebola virus using the antibodies and antigen binding fragments are disclose...

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Main Authors TREFRY, John, CORTI, Davide, GRAHAM, Barney, MUYEMBE-TAMFUN, Jean-Jacques, STANLEY, Daphne, LANZAVECCHIA, Antonio, LEDGERWOOD, Julie, SULLIVAN, Nancy, MULANGU, Sabue
Format Patent
LanguageEnglish
French
German
Published 08.09.2021
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:Neutralizing antibodies and antigen binding fragments that specifically bind to Ebola virus glycoprotein are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. Methods for detecting Ebola virus using the antibodies and antigen binding fragments are disclosed. The antibodies, antigen binding fragments, nucleic acids, and vectors, can be used, for example, to prevent and/or treat Ebola virus infection in a subject.
Bibliography:Application Number: EP20210158309