NONAPEPTIDE PREVENTING INCREASED HYPERPERMEABILITY OF VASCULAR ENDOTHELIUM

The invention relates to a low-toxicity, proteolysis-resistant biologically active nonapeptide of formula (I) that is capable of preventing vascular hyperpermeability in stressful situations. Owing to said property, the claimed peptide can be used in medicine as an anti-edematous agent.

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Bibliographic Details
Main Authors SAMSONOV, Mikhail Vasilievich, MOLOKOEDOV, Aleksandr Sergeevich, KAZAKOVA, Olga Alekseevna, KHAPCHAEV, Asker Yusufovich, AZMUKO, Andrey Andreevich, OVCHINNIKOV, Mihail Vladimirovich, SHIRINSKY, Vladimir Pavlovich, ARZAMASCEV, Yevgeniy Veniaminovich, BUSHUEV, Valeri Nikolaevich, TEREKHOVA, Olga Alexandrovna, PALKEEVA, Marina Yevgenievna, SIDOROVA, Mariya Vladimirovna
Format Patent
LanguageEnglish
French
German
Published 07.09.2022
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to a low-toxicity, proteolysis-resistant biologically active nonapeptide of formula (I) that is capable of preventing vascular hyperpermeability in stressful situations. Owing to said property, the claimed peptide can be used in medicine as an anti-edematous agent.
Bibliography:Application Number: EP20190866300