PROCESSES FOR DELIVERY OF VISCOUS DRUG THERAPIES

Core annular flow is used to enable the subcutaneous delivery of a viscous fluid such as a protein therapeutic formulation. The high-viscosity fluid is surrounded by a low-viscosity fluid, and the low-viscosity fluid lubricates the passage of the high- viscosity fluid. This allows the use of pro - t...

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Bibliographic Details
Main Authors RISSER, Steven, M, SCRIBBEN, Eric, C, CLAY, John, D, BLUM, Timothy, M, ELLIS, Jeffrey, L, HEINTZ, Amy, M
Format Patent
LanguageEnglish
French
German
Published 28.07.2021
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Summary:Core annular flow is used to enable the subcutaneous delivery of a viscous fluid such as a protein therapeutic formulation. The high-viscosity fluid is surrounded by a low-viscosity fluid, and the low-viscosity fluid lubricates the passage of the high- viscosity fluid. This allows the use of pro - tein formulations that have a higher concentration and a higher viscosity at comparatively reduced injection forces and reduced injection times. Several different embodiments of injection devices that provide core annular flow are described herein.
Bibliography:Application Number: EP20210157891