TREATING SICKLE CELL DISEASE WITH A PYRUVATE KINASE R ACTIVATING COMPOUND

Compounds that activate pyruvate kinase R can be used for the treatment of sickle cell disease (SCD). Methods and compositions for the treatment of SCD are provided herein, including a therapeutic compound designated as Compound 1.

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Bibliographic Details
Main Authors MARSHALL, Gary, GREEN, Neal, WANG, Zhongguo, RIBADENEIRA, Maria, SCHROEDER, Patricia, ERICSSON, Anna, MITCHELL, Lorna, GUSTAFSON, Gary, RICHARD, David, KELLY, Patrick, F, LANCIA, David R., Jr, MONDAL, Madhu, FORSYTH, Sanjeev
Format Patent
LanguageEnglish
French
German
Published 20.07.2022
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Compounds that activate pyruvate kinase R can be used for the treatment of sickle cell disease (SCD). Methods and compositions for the treatment of SCD are provided herein, including a therapeutic compound designated as Compound 1.
Bibliography:Application Number: EP20190863246