SUBSTITUTED INDOLES AND METHODS OF USE THEREOF

The present disclosure provides substituted indole compounds of Formula I: (I) and the pharmaceutically acceptable salts and solvates thereof, wherein R1a, R1e, G1, G2, Q1, Q2, Q3, and (II) are defined as set forth in the specification. The present disclosure is also directed to the use of compounds...

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Bibliographic Details
Main Authors FOLEY, Megan Alene Cloonan, LAMPE, John, REITER, Lawrence Alan, DUNCAN, Kenneth, MUNCHHOF, Michael John, HARVEY, Darren Martin, THOMENIUS, Michael, CAMPBELL, John
Format Patent
LanguageEnglish
French
German
Published 23.06.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The present disclosure provides substituted indole compounds of Formula I: (I) and the pharmaceutically acceptable salts and solvates thereof, wherein R1a, R1e, G1, G2, Q1, Q2, Q3, and (II) are defined as set forth in the specification. The present disclosure is also directed to the use of compounds of Formula I to treat a disease, disorder, or condition such as cancer in a subject.
Bibliography:Application Number: EP20190849109