NOVEL CRISPR-ASSOCIATED PROTEIN AND USE THEREOF

The present invention relates to a novel CRISPR-associated protein and a use thereof. A protein represented by an amino acid sequence of SEQ ID NO: 1 or SEQ ID NO: 3, according to the present invention, exhibits the activity of endonucleases, which recognize and cleave an intracellular nucleic acid...

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Bibliographic Details
Main Authors KIM, Dong Wook, YOON, Jiyoung, KIM, Han Seong, PARK, Jongjin, CHOE, Sunghwa
Format Patent
LanguageEnglish
French
German
Published 16.06.2021
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:The present invention relates to a novel CRISPR-associated protein and a use thereof. A protein represented by an amino acid sequence of SEQ ID NO: 1 or SEQ ID NO: 3, according to the present invention, exhibits the activity of endonucleases, which recognize and cleave an intracellular nucleic acid sequence linked to a guide RNA. Therefore, a novel CRISPR-associated protein of the invention can be used as a different nuclease for genome editing, in a CRISPR-Cas system.
Bibliography:Application Number: EP20190846625