COMPOUNDS FOR TREATING AND PREVENTING GROWTH HORMONE RECEPTOR-DEPENDENT CONDITIONS

The invention relates to compounds, in particular pyrimidine-2,4-diamines, analogues and salts thereof and pharmaceutical compositions comprising pyrimidine-2,4-diamines analogues and salts thereof for use in the treatment and prevention of a disease, in particular a growth hormone receptor-dependen...

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Main Authors PIET, Dennis Patrick, DE KLERK-SPRENKELS, Nanda Elisabeth, VAN DER VELDEN, Lieke Maria, VIËTOR, Hendrik Engelbertus, STROUS, Gerardus Jacobus Antonius Maria, MOL, Jan Adrianus, KLUMPERMAN, Judith, TIJHUIS, Johann Heinrich, VAN DER KRIFT, Felix, MAAS, Petrus Emmanuel Marie, MAURICE, Madelon Maria
Format Patent
LanguageEnglish
French
German
Published 28.04.2021
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to compounds, in particular pyrimidine-2,4-diamines, analogues and salts thereof and pharmaceutical compositions comprising pyrimidine-2,4-diamines analogues and salts thereof for use in the treatment and prevention of a disease, in particular a growth hormone receptor-dependent condition. The invention also relates to methods of using these compounds and compositions to treat physiological dsorders related to the amount or activity of growth hormone. In a particular embodiment, the invention relates to a compound according to formula 1 for use in the treatment or prevention of a disease in a subject
Bibliography:Application Number: EP20190205268