ANTIBODIES THAT BIND TUMOR TISSUE FOR DIAGNOSIS AND THERAPY

Provided herein are antibodies that bind to tumor tissue through a binding interaction with an extracellular RNA-protein complex. Such antibodies are used in methods of inducing an immune response and methods of inhibiting tumor cell growth. Additionally provided are methods of producing such antibo...

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Bibliographic Details
Main Authors EMERLING, Daniel Eric, LIU, Fengling, FINN, Jessica, SCHOLZ, Alexander, ROBINSON, William H, HUANG, Vera, MANNING-BOG, Amy, SERAFINI, Tito, TAN, Yann Chong, DEFALCO, Jeff, GREENBERG, Norman Michael, VAD, Nikhil, VOLKMUTH, Wayne, LIPPOW, Shaun M
Format Patent
LanguageEnglish
French
German
Published 21.04.2021
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Provided herein are antibodies that bind to tumor tissue through a binding interaction with an extracellular RNA-protein complex. Such antibodies are used in methods of inducing an immune response and methods of inhibiting tumor cell growth. Additionally provided are methods of producing such antibodies.
Bibliography:Application Number: EP20200712121