METHODS OF INHIBITING PROLIFERATIVE CELLS
The present invention provides methods of negatively modulating the Werner protein (WRN) to inhibit proliferative cells characterized by high microsatellite instability (MSI-H), for example to treat proliferative diseases (such as cancer) characterized by high MSI (MSI-H). Further provided are compo...
Saved in:
Main Authors | , , , |
---|---|
Format | Patent |
Language | English French German |
Published |
21.04.2021
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | The present invention provides methods of negatively modulating the Werner protein (WRN) to inhibit proliferative cells characterized by high microsatellite instability (MSI-H), for example to treat proliferative diseases (such as cancer) characterized by high MSI (MSI-H). Further provided are compositions used in such methods. |
---|---|
Bibliography: | Application Number: EP20190735074 |