IRE-1A INHIBITORS

Compounds which directly inhibit IRE-1α activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof. Such compounds and prodrugs are useful for treating diseases associated with the unfolded protein response or with regulated IRE1-dependent decay (RIDD) and can be used as single agent...

Full description

Saved in:
Bibliographic Details
Main Authors WADE, Warren Stanfield, ZENG, Qingping, PATTERSON, John, Bruce, ZUBOVICS, Zoltan, YANG, Yun, WU, Zhipeng, TORO, Andras
Format Patent
LanguageEnglish
French
German
Published 07.04.2021
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

Abstract Compounds which directly inhibit IRE-1α activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof. Such compounds and prodrugs are useful for treating diseases associated with the unfolded protein response or with regulated IRE1-dependent decay (RIDD) and can be used as single agents or in combination therapies.
AbstractList Compounds which directly inhibit IRE-1α activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof. Such compounds and prodrugs are useful for treating diseases associated with the unfolded protein response or with regulated IRE1-dependent decay (RIDD) and can be used as single agents or in combination therapies.
Author PATTERSON, John, Bruce
ZUBOVICS, Zoltan
WADE, Warren Stanfield
ZENG, Qingping
TORO, Andras
YANG, Yun
WU, Zhipeng
Author_xml – fullname: WADE, Warren Stanfield
– fullname: ZENG, Qingping
– fullname: PATTERSON, John, Bruce
– fullname: ZUBOVICS, Zoltan
– fullname: YANG, Yun
– fullname: WU, Zhipeng
– fullname: TORO, Andras
BookMark eNrjYmDJy89L5WQQ9Axy1TV0VPD08_B08gzxDwrmYWBNS8wpTuWF0twMCm6uIc4euqkF-fGpxQWJyal5qSXxrgHG5paWFuYGjobGRCgBAJQ9Hw4
ContentType Patent
DBID EVB
DatabaseName esp@cenet
DatabaseTitleList
Database_xml – sequence: 1
  dbid: EVB
  name: esp@cenet
  url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP
  sourceTypes: Open Access Repository
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
Chemistry
Sciences
DocumentTitleAlternate IRE-1A-INHIBITOREN
INHIBITEURS DE IRE-1A
ExternalDocumentID EP3799870A1
GroupedDBID EVB
ID FETCH-epo_espacenet_EP3799870A13
IEDL.DBID EVB
IngestDate Fri Jul 19 13:05:15 EDT 2024
IsOpenAccess true
IsPeerReviewed false
IsScholarly false
Language English
French
German
LinkModel DirectLink
MergedId FETCHMERGED-epo_espacenet_EP3799870A13
Notes Application Number: EP20200209114
OpenAccessLink https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210407&DB=EPODOC&CC=EP&NR=3799870A1
ParticipantIDs epo_espacenet_EP3799870A1
PublicationCentury 2000
PublicationDate 20210407
PublicationDateYYYYMMDD 2021-04-07
PublicationDate_xml – month: 04
  year: 2021
  text: 20210407
  day: 07
PublicationDecade 2020
PublicationYear 2021
RelatedCompanies Fosun Orinove Pharmatech, Inc
RelatedCompanies_xml – name: Fosun Orinove Pharmatech, Inc
Score 3.3199413
Snippet Compounds which directly inhibit IRE-1α activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof. Such compounds and prodrugs are useful for...
SourceID epo
SourceType Open Access Repository
SubjectTerms HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title IRE-1A INHIBITORS
URI https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210407&DB=EPODOC&locale=&CC=EP&NR=3799870A1
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfZ3NS8MwFMAfY4p6m1NxftGD9FZsmtquhyLrF62wttQqu42kyWCXOVzFf9-30E0vegsJPPISXl5-Sd4LwL3JJKUNzgAhDQKKZJbBnbEwuET_whpOhPobcJo76av9PHuc9WC5i4VReUK_VHJEtKgG7b1V6_X65xArUm8rNw98iVXvT0ntR3pHx8gvCCh6FPhxWURFqIchlvS88qmLXOGaEwSlA9xFu4rZ3oJtUMr6t0dJBnBYorBVewo9uRrCcbj7eG0IR9PuvhuLneltzmCQVbFBJlqWp1mQ1UX1cg5aEtdhaqDs-V6PeVzue0EvoI94Ly9BY4sxY4Ix2xHEFpbLPG4LTr2FoJ5jSXMEoz_FXP3Tdg0n2wFRr0zcG-i3H5_yFh1oy--U6t8dUHLE
link.rule.ids 230,309,783,888,25577,76883
linkProvider European Patent Office
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfZ07T8MwEIBPVUGUrRQQ5ZkBZYvIq3kMEWpeSqBJqhJQt8iOXalLqWgQf5-rlRYW2E62dPJD5_Nn-84A9yrhhlHjDGhajYDCia5Qy2EK5ehfSE01Jv4GzHIreTWf5qN5B5a7WBiRJ_RLJEdEi6rR3huxXq9_DrFC8bZy80CXWPT-GJdeKLd0jPyCgCKHvhdNi7AI5CBASc5nnmEjV9jqGEHpAHfYjiClN38blLL-7VHiPhxOUdmqOYEOXw2gF-w-XhvAUdbed6PYmt7mFPrpLFK0sZTmSeqnZTF7OQMpjsogUVB3te9HFU33rTDOoYt4zy9AIguHEEaIaTHNZLpNXGoyargLZriWztUhDP9Uc_lP3R30kjKbVJM0f76C4-3giBcn9jV0m49PfoPOtKG3Yhi-AaYDdbQ
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=IRE-1A+INHIBITORS&rft.inventor=WADE%2C+Warren+Stanfield&rft.inventor=ZENG%2C+Qingping&rft.inventor=PATTERSON%2C+John%2C+Bruce&rft.inventor=ZUBOVICS%2C+Zoltan&rft.inventor=YANG%2C+Yun&rft.inventor=WU%2C+Zhipeng&rft.inventor=TORO%2C+Andras&rft.date=2021-04-07&rft.externalDBID=A1&rft.externalDocID=EP3799870A1