METHODS FOR CONTROLLING PHA BIOSYNTHESIS IN CUPRIAVIDUS OR RALSTONIA

Provided herein are methods for increasing the yield of an extracellular product synthesized by an organism cultured in a continuous aerobic fermentation system. The extracellular product yield is increased through the use of an organism modified to decreased production of polyhydroxyalkanoate, to i...

Full description

Saved in:
Bibliographic Details
Main Authors TAYLOR, Mark Paul, AMATRIAIN, Cristina Serrano, PEARLMAN, Paul Sheldon, FOSTER, Alexander Brett, SMITH, Gary J
Format Patent
LanguageEnglish
French
German
Published 10.03.2021
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
SPIRITS
VINEGAR
WINE
Online AccessGet full text

Cover

More Information
Summary:Provided herein are methods for increasing the yield of an extracellular product synthesized by an organism cultured in a continuous aerobic fermentation system. The extracellular product yield is increased through the use of an organism modified to decreased production of polyhydroxyalkanoate, to increase production of the extracellular product, and to include promoters that can be inducible in response to nutrient limitation conditions. The extracellular product yield is also increased by operating the continuous fermentation system under particular nutrient limitation conditions. Also provided are non-naturally occurring organisms that have been modified for use with the provided methods, and extracellular products made using the provided methods.
Bibliography:Application Number: EP20190724310