GIP DERIVATIVES AND USES THEREOF

The present invention relates to novel peptides that are derivatives of glucose-dependent insulinotropic polypeptide (GIP) analogues having improved physical stability in solution and a protracted profile of action. More particular the invention relates to such peptides that are agonists at the GIP...

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Main Authors FINAN, Brian, LAU, Jesper F, HOGENDORF, Wouter Frederik Johan, COX, Nicholas Raymond, THØGERSEN, Henning, KNERR, Patrick J, REEDTZ-RUNGE, Steffen, DIMARCHI, Richard, LIU, Fa
Format Patent
LanguageEnglish
French
German
Published 09.08.2023
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates to novel peptides that are derivatives of glucose-dependent insulinotropic polypeptide (GIP) analogues having improved physical stability in solution and a protracted profile of action. More particular the invention relates to such peptides that are agonists at the GIP receptor and to their use in weight management or for treatment of diseases such as obesity, diabetes or non-alcoholic steatohepatitis (NASH).
Bibliography:Application Number: EP20190722582