SUSTAINED RELEASE FORMULATIONS OF DYSOXYLUM BINECTARIFERUM

The present invention relates to the novel formulation for sustained or delayed release of rohitukine-rich Dysoxylum binectariferum extract/fraction and a process for preparing the same wherein the extract is wet-granulated using excipients i.e. biodegradable polymers and/or non-biodegradable polyme...

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Bibliographic Details
Main Authors KUMAR, Ajay, VISHWAKARMA, Ram, BHARATE, Sonali Sandip, GANDHI, Sumit, BHARATE, Sandip Bibishan, KUMAR, Vikas, GUPTA, Mehak
Format Patent
LanguageEnglish
French
German
Published 24.02.2021
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates to the novel formulation for sustained or delayed release of rohitukine-rich Dysoxylum binectariferum extract/fraction and a process for preparing the same wherein the extract is wet-granulated using excipients i.e. biodegradable polymers and/or non-biodegradable polymers alone or in combination, and the said granules are either filled into a capsule or compressed into a tablet. The said formulation comprising a granulated extract/fraction of rohitukine-rich Dysoxylum binectariferum with polymers has resulted in a sustained release of the extract or fraction over a period of 16-24 hrs. The said formulations are useful in the treatment of inflammatory diseases.
Bibliography:Application Number: EP20190723887