HYDROPHILIC BERBERINE-TYPE DERIVATIVE AND APPLICATION THEREOF IN PREPARING DRUG

An 8-dihalomethyl berberine-type quaternary ammonium salt compound represented by general formula (I) or (II) and an application thereof in preparing a drug. The compound shows hydrophilicity and has antimicrobial, anti-inflmmatory, anti-ulcerative colitis, and antitumor activities, while having no...

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Main Authors QIN, Hailin, LI, Zhihong, ZHANG, Haijing, ZHANG, Zhihui, LI, Xiang, DENG, Anjun, TANG, Xiaonan, WU, Lianqiu, SONG, Huachen, SONG, Li
Format Patent
LanguageEnglish
French
German
Published 30.06.2021
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:An 8-dihalomethyl berberine-type quaternary ammonium salt compound represented by general formula (I) or (II) and an application thereof in preparing a drug. The compound shows hydrophilicity and has antimicrobial, anti-inflmmatory, anti-ulcerative colitis, and antitumor activities, while having no or low toxicity.
Bibliography:Application Number: EP20190784977