USE OF CCR3-INHIBITORS FOR TREATING DRY AGE-RELATED MACULAR DEGENERATION

The present invention relates to CCR3 inhibitors of formula 1,whereinR1is H, C1-6-alkyl, C0-4-alkyl-C3-6-cycloalkyl, C1-6-haloalkyl;R2is H, C1-6-alkyl;Xis an anion selected from the group consisting of chloride or ½ dibenzoyltartratejis 1 or 2.for use as a medicament for the treatment of diseases se...

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Bibliographic Details
Main Authors BOUYSSOU, Thierry, NIVENS, Michael Chadham, GOEGGEL, Rolf, SEITHER, Peter
Format Patent
LanguageEnglish
French
German
Published 28.02.2024
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to CCR3 inhibitors of formula 1,whereinR1is H, C1-6-alkyl, C0-4-alkyl-C3-6-cycloalkyl, C1-6-haloalkyl;R2is H, C1-6-alkyl;Xis an anion selected from the group consisting of chloride or ½ dibenzoyltartratejis 1 or 2.for use as a medicament for the treatment of diseases selected from dry age-related macular degeneration (dAMD), wet age-related macular degeneration (wAMD), retinopathy of prematurity (ROP), central retinal vein occlusion (CRVO), nasal polyposis, eosinophilic esophagitis, eosinophillic gastroenteritis (e.g. eosinophilic gastritis and eosinophilic ententeritis), hypereosinophilic syndrome and Churg Strauss syndrome.
Bibliography:Application Number: EP20200174399