INDANE-AMINES AS PD-L1 ANTAGONISTS

• Main Authors: PUNNA, Sreenivas, LANGE, Christopher, SINGH, Rajinder, ZHANG, Penglie, YANG, Ju
• Format: Patent
• Language: English; French; German
• Published: 30.12.2020
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

Compounds are provided that are useful as immunomodulators. The compounds have the Formula (I)including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1, R2a, R2b, R2c, R3, R4, R5, R6a, R6b, m and n are as defined herein. Methods associated with preparation and use of such com...