INDANE-AMINES AS PD-L1 ANTAGONISTS

Compounds are provided that are useful as immunomodulators. The compounds have the Formula (I)including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1, R2a, R2b, R2c, R3, R4, R5, R6a, R6b, m and n are as defined herein. Methods associated with preparation and use of such com...

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Bibliographic Details
Main Authors PUNNA, Sreenivas, LANGE, Christopher, SINGH, Rajinder, ZHANG, Penglie, YANG, Ju
Format Patent
LanguageEnglish
French
German
Published 30.12.2020
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Compounds are provided that are useful as immunomodulators. The compounds have the Formula (I)including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1, R2a, R2b, R2c, R3, R4, R5, R6a, R6b, m and n are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
Bibliography:Application Number: EP20190757004