THERAPEUTIC MOLECULES THAT BIND TO LAG3 AND PD1

The invention relates to LAG-3 binding agents, in particular particularly variable heavy chain (VH) sdAbs and bispecific agents that target both LAG-3 and PD-1, and the use of such binding agents in the treatment, prevention and detection of disease.

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Bibliographic Details
Main Authors LEGG, James, SETTE, Angelica, TENG, Yumin, OSUCH, Isabelle, EDWARDS, Carolyn, ESCORS MURUGARREN, David
Format Patent
LanguageEnglish
French
German
Published 23.12.2020
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to LAG-3 binding agents, in particular particularly variable heavy chain (VH) sdAbs and bispecific agents that target both LAG-3 and PD-1, and the use of such binding agents in the treatment, prevention and detection of disease.
Bibliography:Application Number: EP20190707094