POLYCYCLIC COMPOUNDS AS ALLOSTERIC SHP2 INHIBITORS

The present disclosure is directed to inhibitors of SHP2 and their use in the treatment of disease. Also disclosed are pharmaceutical compositions comprising the same.

Saved in:
Bibliographic Details
Main Authors WON, Walter S, LI, Jie Jack, AAY, Naing N, KOLTUN, Elena S, BLANK, Brian R, TZITZILONIS, Christos, PITZEN, Jennifer, BUCKL, Andreas, WANG, Gang, JOGALEKAR, Ashutosh S, MELLEM, Kevin T, GILL, Adrian Liam, CREGG, James Joseph
Format Patent
LanguageEnglish
French
German
Published 21.10.2020
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:The present disclosure is directed to inhibitors of SHP2 and their use in the treatment of disease. Also disclosed are pharmaceutical compositions comprising the same.
Bibliography:Application Number: EP20180830634