3'END CAPS FOR RNA-INTERFERRING AGENTS FOR USE IN RNA
The disclosure relates to novel compounds and compositions comprising a RNAi agent comprising a novel compound as a 3' end cap. The disclosure also relates to processes for making such compositions, and methods and uses of such compositions, e.g., to mediate RNA interference.
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Main Authors | , , , , , , , , , , , , , |
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Format | Patent |
Language | English French German |
Published |
14.10.2020
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Subjects | |
Online Access | Get full text |
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Abstract | The disclosure relates to novel compounds and compositions comprising a RNAi agent comprising a novel compound as a 3' end cap. The disclosure also relates to processes for making such compositions, and methods and uses of such compositions, e.g., to mediate RNA interference. |
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AbstractList | The disclosure relates to novel compounds and compositions comprising a RNAi agent comprising a novel compound as a 3' end cap. The disclosure also relates to processes for making such compositions, and methods and uses of such compositions, e.g., to mediate RNA interference. |
Author | ZHU, Meicheng HUESKEN, Dieter FERNANDEZ, Cesar PATNAIK, Anup GREENIDGE, Paulette HUNZIKER, Juerg BARYZA, Jeremy Lee BLOMMERS, Marcel RONDEAU, Jean-Michel Rene NATT, Francois Jean-Charles GENO, Erin GOSSERT, Alvar PATTERSON, Andrew WEILER, Jan |
Author_xml | – fullname: ZHU, Meicheng – fullname: BLOMMERS, Marcel – fullname: GREENIDGE, Paulette – fullname: HUNZIKER, Juerg – fullname: WEILER, Jan – fullname: HUESKEN, Dieter – fullname: FERNANDEZ, Cesar – fullname: PATNAIK, Anup – fullname: PATTERSON, Andrew – fullname: GOSSERT, Alvar – fullname: NATT, Francois Jean-Charles – fullname: GENO, Erin – fullname: BARYZA, Jeremy Lee – fullname: RONDEAU, Jean-Michel Rene |
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DocumentTitleAlternate | 3 EMBOUTS POUR DES AGENTS ARNI UTILISÉS DANS L'ARN 3'-ENDKAPPEN FÜR RNA-INTERFERENZ-WIRKSTOFFE ZUR VERWENDUNG IN RNA |
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Notes | Application Number: EP20200160770 |
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RelatedCompanies | Novartis AG |
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Snippet | The disclosure relates to novel compounds and compositions comprising a RNAi agent comprising a novel compound as a 3' end cap. The disclosure also relates to... |
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Title | 3'END CAPS FOR RNA-INTERFERRING AGENTS FOR USE IN RNA |
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