3'END CAPS FOR RNA-INTERFERRING AGENTS FOR USE IN RNA

The disclosure relates to novel compounds and compositions comprising a RNAi agent comprising a novel compound as a 3' end cap. The disclosure also relates to processes for making such compositions, and methods and uses of such compositions, e.g., to mediate RNA interference.

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Bibliographic Details
Main Authors ZHU, Meicheng, BLOMMERS, Marcel, GREENIDGE, Paulette, HUNZIKER, Juerg, WEILER, Jan, HUESKEN, Dieter, FERNANDEZ, Cesar, PATNAIK, Anup, PATTERSON, Andrew, GOSSERT, Alvar, NATT, Francois Jean-Charles, GENO, Erin, BARYZA, Jeremy Lee, RONDEAU, Jean-Michel Rene
Format Patent
LanguageEnglish
French
German
Published 14.10.2020
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HETEROCYCLIC COMPOUNDS
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The disclosure relates to novel compounds and compositions comprising a RNAi agent comprising a novel compound as a 3' end cap. The disclosure also relates to processes for making such compositions, and methods and uses of such compositions, e.g., to mediate RNA interference.
Bibliography:Application Number: EP20200160770