PREPARATION FOR MAGNETIC RESONANCE DIAGNOSTICS FOR ONCOLOGICAL DISEASES, COMPRISING DEUTERATED 3-O-METHYLGLUCOSE, AND DIAGNOSTIC METHOD USING SAID PREPARATION

The invention relates to medicine, namely to the means for magnetic resonance imaging of the oncological diseases. For this purpose, the diagnostic agent and the diagnostic method based on the use of the diagnostic agent is developed, which is based on a deuterated derivative of 3-O-methylglucose or...

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Bibliographic Details
Main Authors IVASHKIN, Pavel Evgenievich, DOROFEEVA, Evgeniya Olegovna, POLSHAKOV, Vladimir Ivanovich, KOSENKOV, Aleksei Viktorovich, LESIV, Aleksei Valerievich, GULYAEV, Mikhail Vladimirovich, KISELEVSKY, Mikhail Valentinovich
Format Patent
LanguageEnglish
French
German
Published 19.05.2021
Subjects
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SUGARS
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Summary:The invention relates to medicine, namely to the means for magnetic resonance imaging of the oncological diseases. For this purpose, the diagnostic agent and the diagnostic method based on the use of the diagnostic agent is developed, which is based on a deuterated derivative of 3-O-methylglucose or a mixture of at least two different deuterated derivatives of 3-O-methylglucose. The method of the invention involves performing magnetic resonance imaging and/or magnetic resonance spectroscopy at the frequency of deuterium nuclei after administration of the diagnostic medication after a time sufficient for accumulation of the diagnostic medication in the tumor tissue of a subject for receiving, respectively, MR images and/or MR spectra.The proposed method allows diagnosing oncological diseases with high informational content.
Bibliography:Application Number: EP20170932983