GENETICALLY ENCODED CALCIUM INDICATORS AND METHODS OF USE

Genetically encoded calcium indicator (GECI) polypeptides and the nucleic acid molecules encoding such polypeptides are provided. In addition, methods of using such nucleic acids and polypeptides in methods of screening for agonists or antagonists of G-protein coupled receptor (GPCR) or ion channels...

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Bibliographic Details
Main Authors SCHREITER, Eric, KIM, Douglas, SVOBODA, Karel, LOOGER, Loren
Format Patent
LanguageEnglish
French
German
Published 11.08.2021
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Summary:Genetically encoded calcium indicator (GECI) polypeptides and the nucleic acid molecules encoding such polypeptides are provided. In addition, methods of using such nucleic acids and polypeptides in methods of screening for agonists or antagonists of G-protein coupled receptor (GPCR) or ion channels and methods of monitoring neural activity also are provided.
Bibliography:Application Number: EP20180882227