POLYMERASE VARIANTS AND USES THEREOF

Described herein is a variant pol6 polymerase having at least one mutation selected from H223, N224, Y225, H227, I295, Y342, T343, I357, S360, L361, I363, S365, S366, Y367, P368, D417, E475, Y476, F478, K518, H527, T529, M531, N535, G539, P542, N545, Q546, A547, L549, I550, N552, G553, F558, A596, G...

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Main Authors Boenitz-Dulat, Mara, Schwab, Charles, Wayan, Thai, Eileen, Ayer, Aruna, Woersdoerfer, Bigna, Eckert, Barbara, McGaw, Colin, Lederman, Ilya, Suko, Shawn, Bibillo, Arkadiusz, Cleoma, Arnold, Schultz, Tyler, Wunderlich, David
Format Patent
LanguageEnglish
French
German
Published 23.09.2020
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Summary:Described herein is a variant pol6 polymerase having at least one mutation selected from H223, N224, Y225, H227, I295, Y342, T343, I357, S360, L361, I363, S365, S366, Y367, P368, D417, E475, Y476, F478, K518, H527, T529, M531, N535, G539, P542, N545, Q546, A547, L549, I550, N552, G553, F558, A596, G603, A610, V615, Y622, C623, D624, I628, Y629, R632, N635, M641, A643, I644, T647, I648, T651, I652, K655, W656, D657, V658, H660, F662, L690 and combinations thereof.
Bibliography:Application Number: EP20200165815