MODULATORS OF CELL ADHESION, METHODS AND COMPOSITIONS THEREFOR
Compounds with activity as modulators of cell adhesion are disclosed. The compounds are derivatives of piperidin-4-amine. In some embodiments, a compound can be linked to a targeting agent, a pharmaceutically active substance and/or a support material. Methods for enhancing or inhibiting classical c...
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Main Authors | , |
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Format | Patent |
Language | English French German |
Published |
07.06.2023
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Subjects | |
Online Access | Get full text |
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Summary: | Compounds with activity as modulators of cell adhesion are disclosed. The compounds are derivatives of piperidin-4-amine. In some embodiments, a compound can be linked to a targeting agent, a pharmaceutically active substance and/or a support material. Methods for enhancing or inhibiting classical cadherin-mediated functions are also disclosed. The compounds can be used for the treatment or prevention of a variety of diseases including cancer. Compositions and devices, including skin patches comprising a compound are also disclosed. In addition, methods of synthesis of the compounds are provided. |
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Bibliography: | Application Number: EP20180792765 |