PSMA-TARGETING AMANITIN CONJUGATES

The invention relates to a PSMA-targeting conjugate comprising (a) an amatoxin; (b) a small molecule PSMA-targeting moiety; and (c) optionally a linker linking said amatoxin and said small molecule PSMA-targeting moiety. The invention furthermore relates to a pharmaceutical composition comprising su...

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Bibliographic Details
Main Authors GALLO, Francesca, LUTZ, Christian, KULKE, Michael, MUELLER, Christoph, HECHLER, Torsten, PAHL, Andreas, SIMON, Werner, KORSAK, Barbara
Format Patent
LanguageEnglish
French
German
Published 29.07.2020
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention relates to a PSMA-targeting conjugate comprising (a) an amatoxin; (b) a small molecule PSMA-targeting moiety; and (c) optionally a linker linking said amatoxin and said small molecule PSMA-targeting moiety. The invention furthermore relates to a pharmaceutical composition comprising such conjugate.
Bibliography:Application Number: EP20180773188