8-[6-[3-(AMINO)PROPOXY]-3-PYRIDYL]-1-ISOPROPYL-IMIDAZO[4,5-C]QUINOLIN-2-ONE DERIVATIVES AS SELECTIVE MODULATORS OF ATAXIA TELANGIECTASIA MUTATED (ATM) KINASE FOR THE TREATMENT OF HUNTINGTON'S DISEASE

The specification generally relates to compounds of Formula(I):and pharmaceutically acceptable salts thereof, whereR1,R2,R3,R4andR5have any of the meanings defined herein, for use in the treatment of Huntington's disease.

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Bibliographic Details
Main Authors PIKE, Kurt, Gordon, HUNT, Thomas Anthony, BARLAAM, Bernard Christophe, EATHERTON, Andrew John
Format Patent
LanguageEnglish
French
German
Published 13.04.2022
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The specification generally relates to compounds of Formula(I):and pharmaceutically acceptable salts thereof, whereR1,R2,R3,R4andR5have any of the meanings defined herein, for use in the treatment of Huntington's disease.
Bibliography:Application Number: EP20200156172