NOVEL HETEROCYCLIC COMPOUNDS AS CDK8/19 INHIBITORS

The present invention relates to novel compounds of formula (I):or a pharmaceutically acceptable salt or stereoisomer thereof, which exhibit the properties of a CDK 8/19 inhibitor. The invention also relates to a pharmaceutical composition containing said compounds and to the use thereof as pharmace...

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Main Authors KASATKINA, Mariia Andreevna, CHESTNOVA, Anna Jur'evna, GORBUNOVA, Svetlana Leonidovna, ZAVIALOV, Kirill Vadimovich, KOZHEMYAKINA, Natalia Vladimirovna, POPKOVA, Aleksandra Vladimirovna, ALAFINOV, Andrei Ivanovich, IAKOVLEV, Pavel Andreevich, KUSHAKOVA, Anna Sergeevna, MOROZOV, Dmitry Valentinovich, MINDICH, Aleksei Leonidovich, SHEKHAUTSOU, Artsiom Evgenievich, ALESHUNIN, Pavel Aleksandrovich, REKHARSKY, Mikhail Vladimirovich, EVDOKIMOV, Anton Aleksandrovich, MAKSIMENKO, Elena Aleksandrovna, MISHINA, Mariia Sergeevna
Format Patent
LanguageEnglish
French
German
Published 17.06.2020
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to novel compounds of formula (I):or a pharmaceutically acceptable salt or stereoisomer thereof, which exhibit the properties of a CDK 8/19 inhibitor. The invention also relates to a pharmaceutical composition containing said compounds and to the use thereof as pharmaceutical drugs for treating diseases or disorders.
Bibliography:Application Number: EP20180843992