mTOR ENHACERS AND USES THEREOF TO IMPROVE SPERM QUALITY AND FUNCTION DURING STORAGE

The present invention refers to field of assisted reproductive technologies, in particular to a sperm storage media, and describes mTOR enhancers, preferably the mTOR activator MHY 1485, as supplement for storage media, said supplemented media increasing sperm motility and viability during short-ter...

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Main Authors PINTO DE ALMEIDA, Susana Paula, BOLÉO TELES DE JESUS, Tito Miguel, FONTES OLIVEIRA, Carlos Pedro, DA SILVA LEITE DE SOUSA, Mário Manuel, GOUVEIA ALVES, Marco Aurélio
Format Patent
LanguageEnglish
French
German
Published 10.06.2020
Subjects
AGRICULTURE
ANIMAL HUSBANDRY
BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES
FISHING
FORESTRY
HUMAN NECESSITIES
HUNTING
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PEST REPELLANTS OR ATTRACTANTS
PLANT GROWTH REGULATORS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF
TRAPPING
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Summary:The present invention refers to field of assisted reproductive technologies, in particular to a sperm storage media, and describes mTOR enhancers, preferably the mTOR activator MHY 1485, as supplement for storage media, said supplemented media increasing sperm motility and viability during short-term room temperature storage, while sustaining the metabolic rates, without changing its fertilization potential (capacitation) and DNA integrity.
Bibliography:Application Number: EP20180758739