SGC STIMULATORS

Compounds of Formulae I' and I are described, which are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds are also useful for treating, preventing or managing various disorders that are herein disclosed.

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Bibliographic Details
Main Authors NAKAI, Takashi, JIA, James, JUNG, Joon, SHEPPECK, James Edward, LEE, Thomas Wai-Ho, HUDSON, Colleen, MERMERIAN, Ara, IYER, Karthik, LONG, Kimberly Kafadar, PERL, Nicholas Robert, IYENGAR, Rajesh R, RENHOWE, Paul Allen, IM, G-Yoon Jamie, MILNE, George Todd, RENNIE, Glen Robert, YU, Xiang Y, BARDEN, Timothy Claude, CURRIE, Mark G, MOORE, Joel
Format Patent
LanguageEnglish
French
German
Published 19.01.2022
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Compounds of Formulae I' and I are described, which are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds are also useful for treating, preventing or managing various disorders that are herein disclosed.
Bibliography:Application Number: EP20190208775