FUSED RING DERIVATIVE HAVING MGAT-2 INHIBITORY ACTIVITY

The present inventon provides the compound represented by the following formula (I):wherein a moiety represented by formula:isor the like;y is 0 or 1; R1 is hydrogen or the like; R2a and R2b are taken together with an adjacent carbon atom to form ring B; ring B is a substituted or unsubstituted non-...

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Bibliographic Details
Main Authors NODU Kouhei, TATENO Yusuke, MASUDA Kengo, NISHIURA Yuji, HINATA Yu, SASAKI Yoshikazu
Format Patent
LanguageEnglish
French
German
Published 24.02.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present inventon provides the compound represented by the following formula (I):wherein a moiety represented by formula:isor the like;y is 0 or 1; R1 is hydrogen or the like; R2a and R2b are taken together with an adjacent carbon atom to form ring B; ring B is a substituted or unsubstituted non-aromatic carbocycle or the like; R3a is hydrogen or the like; R3b is hydrogen or the like; R4a is represented by formula:: L1 is a single bond or the like; L2 is -C(=O)- or the like; L3 is a single bond or the like; R7 is substituted or unsubstituted alkyl or the like; R4b is substituted or unsubstituted alkyl or the like; R4c is each independently halogen or the like.
Bibliography:Application Number: EP20180831430