RAPID ELICITATION OF BROADLY NEUTRALIZING ANTIBODIES TO HIV ENV

The present disclosure relates to methods for generating broadly neutralizing bovine anti-HIV Env antibodies, compositions comprising the broadly neutralizing bovine antibodies, and methods of treatment or prevention of HIV using the broadly neutralizing bovine antibodies. In certain embodiments, a...

Full description

Saved in:
Bibliographic Details
Main Authors SMIDER, Vaughn, V, BURTON, Dennis, R, WILSON, Ian, SOK, Devin, CRISCITIELLO, Michael, MWANGI, Waithaka
Format Patent
LanguageEnglish
French
German
Published 20.05.2020
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
Online AccessGet full text

Cover

More Information
Summary:The present disclosure relates to methods for generating broadly neutralizing bovine anti-HIV Env antibodies, compositions comprising the broadly neutralizing bovine antibodies, and methods of treatment or prevention of HIV using the broadly neutralizing bovine antibodies. In certain embodiments, a broadly neutralizing bovine antibody comprises a polyclonal F(ab) or F(ab′)2 fragment. In certain embodiments, a broadly neutralizing bovine antibody comprises a humanized bovine monoclonal antibody.
Bibliography:Application Number: EP20180831220