COMPOSITIONS FOR TRANSFECTING MRNA INTO A CELL AND THEIR APPLICATIONS

The present invention relates to compositions for transfecting a messenger RNA (mRNA) into a cell and their applications. The present invention is directed to a composition for transfecting a mRNA into a cell comprising a mRNA, at least one neutral lipid and a cationic lipid of formula (I), whereinR...

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Bibliographic Details
Main Authors STOCK, Fabrice, TOUSSAINT MOREAU, Valérie, ERBACHER, Patrick
Format Patent
LanguageEnglish
French
German
Published 03.08.2022
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The present invention relates to compositions for transfecting a messenger RNA (mRNA) into a cell and their applications. The present invention is directed to a composition for transfecting a mRNA into a cell comprising a mRNA, at least one neutral lipid and a cationic lipid of formula (I), whereinR1R2,R3,R4andR5,(CH2)nandA-are as defined in the description. The present invention also relates to uses of said composition and to a method forin vitrotransfection of live cells.
Bibliography:Application Number: EP20180306417