IDENTIFICATION AND ELIMINATION OF DAMAGED AND/OR SENESCENT CELLS

Identification and elimination of damaged and/or senescent cells. This invention relates to methods of detecting cells over-expressing of Programmed Death Ligand 2 (PD-L2), in particular, damaged and/or senescent cells, and the identification thereof. The invention also extends to the use of antagon...

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Bibliographic Details
Main Authors LLANOS GIRON, Susana, SERRANO MARUGAN, Manuel, CHAIB, Andy Selim
Format Patent
LanguageEnglish
French
German
Published 06.05.2020
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
VINEGAR
WINE
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Summary:Identification and elimination of damaged and/or senescent cells. This invention relates to methods of detecting cells over-expressing of Programmed Death Ligand 2 (PD-L2), in particular, damaged and/or senescent cells, and the identification thereof. The invention also extends to the use of antagonists of Programmed Death Ligand 2 (PD-L2) and Programmed Cell Death Protein 1 (PD-1) interaction, or inhibitors of PD-1 or PD-L2 expression to eliminate damaged and/or senescent cells, which are involved in numerous pathologies and aging, and are also produced as a result of exposure to toxic substances.
Bibliography:Application Number: EP20180735568