MULTIPLEX ASSAY

The present invention provides assays for profiling two or more polypeptides in live cells. In some embodiments, the invention provides multicistronic reporter vectors, acceptor cells for receiving multicistronic reporter vectors, and multireporter cells. Methods of making multicistronic reporter ve...

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Bibliographic Details
Main Authors LACAYO, Catherine I, DE ABREU RIBEIRO, M. Susana G, LUDLAM, Mary J.C
Format Patent
LanguageEnglish
French
German
Published 25.03.2020
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Summary:The present invention provides assays for profiling two or more polypeptides in live cells. In some embodiments, the invention provides multicistronic reporter vectors, acceptor cells for receiving multicistronic reporter vectors, and multireporter cells. Methods of making multicistronic reporter vectors, acceptor cells for receiving multicistronic reporter vectors, and multireporter cells are provided. Libraries and kits comprising multicistronic reporter vectors, acceptor cells for receiving multicistronic reporter vectors, and multireporter cells are provided. Methods of profiling/assaying the multireporter cells and multireporter cell libraries are provided.
Bibliography:Application Number: EP20180731252