IMPROVED EXTENDED RELEASE HIGHLY LOADED DRUG COMPOSITIONS
The disclosed technology provides improved drug compositions that provide increased stability, higher drug loading potential, and suitable drug dissolution properties, and methods of making the same. The composition include: (a) a drug component comprising a therapeutically effective amount of a dru...
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Main Authors | , , , |
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Format | Patent |
Language | English French German |
Published |
11.03.2020
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Subjects | |
Online Access | Get full text |
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Summary: | The disclosed technology provides improved drug compositions that provide increased stability, higher drug loading potential, and suitable drug dissolution properties, and methods of making the same. The composition include: (a) a drug component comprising a therapeutically effective amount of a drug; (b) an extended release component comprising a cross-linked polyacrylic acid polymer that is a carbomer homopolymer, carbomer copolymer, carbomer interpolymer, polycarbophil or a mixture thereof; and (c) a buffering component comprising a magnesium containing buffering agent; wherein the drug component makes up at least 50% by weight of the composition. |
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Bibliography: | Application Number: EP20180725989 |