PHOSPHOLIPID DERIVATIVES AND THEIR USE AS MEDICAMENTS

The present invention relates to 1-acyl-lysophosphatidyl derivatives of general formula I;in which R is C4 to C30 aliphatic hydrocarbyl chain, R1 is selected from H or C1 to C10 alkyl, preferably C1 to C6 alkyl, R2 is selected from H, C10 to C30 acyl or C1 to C10 alkyl, preferably C1 to C6 alkyl, an...

Full description

Saved in:
Bibliographic Details
Main Authors WERNER, Lukas, JANECKOVA, Lucie, STURSA, Jan, DVORAK, Michal, DVORAKOVA, Marta, KARAFIAT, Vit
Format Patent
LanguageEnglish
French
German
Published 12.05.2021
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:The present invention relates to 1-acyl-lysophosphatidyl derivatives of general formula I;in which R is C4 to C30 aliphatic hydrocarbyl chain, R1 is selected from H or C1 to C10 alkyl, preferably C1 to C6 alkyl, R2 is selected from H, C10 to C30 acyl or C1 to C10 alkyl, preferably C1 to C6 alkyl, and R3, when present, is selected from H or C1 to C10 alkyl, preferably C1 to C6 alkyl. These derivatives are intended for the treatment of cancer, in particular melanoma, hepatocarcinoma or GIT carcinomas.
Bibliography:Application Number: EP20180719029