PREPARATION, EXPANSION, AND USES OF ADULT PLURIPOTENT STEM CELLS
Certain relatively small cells present in the periphery blood of mammals can be activated to form pluripotent stem cell populations. These small cells are generally less than five micrometers in diameter and are CD45-positive, and are referred to herein as CD45+ cells or dormant tiny cells. Accordin...
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Main Authors | , , |
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Format | Patent |
Language | English French German |
Published |
12.02.2020
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Subjects | |
Online Access | Get full text |
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Summary: | Certain relatively small cells present in the periphery blood of mammals can be activated to form pluripotent stem cell populations. These small cells are generally less than five micrometers in diameter and are CD45-positive, and are referred to herein as CD45+ cells or dormant tiny cells. Accordingly, provided are cell populations and compositions with enriched dormant tiny cells from blood samples and methods and compositions for activating these dormant tiny cells. Upon differentiation, the activated stem cells can be used for various therapeutic purposes. |
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Bibliography: | Application Number: EP20180780741 |