ANTIPROLIFERATIVE COMPOUNDS AND METHODS OF USE THEREOF

The present application relates to compounds of formula Iwherein R1, R2and R3are as defined herein and such compounds are for use in a method of treating, preventing or managing cancer. Said cancer can be leukemia. Said method can further comprise administering a second agent. Pharmaceutical composi...

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Bibliographic Details
Main Authors LOPEZ-GIRONA, Antonia, CORREA, Matthew Daniel, POURDEHNAD, Michael, HANSEN, Joshua, MULLER, George W, CATHERS, Brian Edwin, MACBETH, Kyle J, RAHEJA, Raj Kumar, Man, Hon-Wah, Khalil, Ehab M
Format Patent
LanguageEnglish
French
German
Published 25.10.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present application relates to compounds of formula Iwherein R1, R2and R3are as defined herein and such compounds are for use in a method of treating, preventing or managing cancer. Said cancer can be leukemia. Said method can further comprise administering a second agent. Pharmaceutical compositions and single unit dosage forms comprising such compounds are also provided.
Bibliography:Application Number: EP20190193334