T CELL RECEPTOR LIKE ANTIBODIES THAT BIND TO P53-MHC CLASS I COMPLEX

Antibodies and fragments thereof which bind to peptide-MHC complexes are disclosed, in particular peptide-MHC complex comprising a peptide of p53 and MHC class I molecule. Also disclosed are compositions comprising such antibodies and fragments, and uses and methods using the same.

Saved in:
Bibliographic Details
Main Authors WANG, Cheng-I, LEE, Wen-Hsin, LOW, Lionel, HUANG, Ching-Wen, WANG, Bei, GOH, Angeline
Format Patent
LanguageEnglish
French
German
Published 15.01.2020
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
TESTING
Online AccessGet full text

Cover

More Information
Summary:Antibodies and fragments thereof which bind to peptide-MHC complexes are disclosed, in particular peptide-MHC complex comprising a peptide of p53 and MHC class I molecule. Also disclosed are compositions comprising such antibodies and fragments, and uses and methods using the same.
Bibliography:Application Number: EP20180763437