COMPOSITIONS AND METHODS FOR IMMUNE REPERTOIRE SEQUENCING
The present disclosure provides methods, compositions, kits, and systems useful in the determination and evaluation of the immune repertoire. In one aspect, target-specific primer panels provide for the effective amplification of sequences of T cell receptor and/or B cell receptor chains with improv...
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Main Authors | , , |
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Format | Patent |
Language | English French German |
Published |
06.04.2022
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Subjects | |
Online Access | Get full text |
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Summary: | The present disclosure provides methods, compositions, kits, and systems useful in the determination and evaluation of the immune repertoire. In one aspect, target-specific primer panels provide for the effective amplification of sequences of T cell receptor and/or B cell receptor chains with improved sequencing accuracy and resolution over the repertoire. Variable regions associated with the immune cell receptor are resolved to effectively portray clonal diversity of a biological sample and/or differences associated with the immune cell repertoire of a biological sample. |
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Bibliography: | Application Number: EP20180709172 |