MICROFLUIDIC SYSTEM AND METHOD WITH TIGHTLY CONTROLLED INCUBATION TIME AND CONDITIONS

The invention relates to a microfluidic system in which the droplets flow through an off-chip delay line in a linear sequential order. This ensures that all the droplets are incubated for the same amount of time and under the same conditions as they flow through the delay line. The invention further...

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Bibliographic Details
Main Authors SHIUE, Eric, DU, Guansheng, LÖFFERT, Dirk
Format Patent
LanguageEnglish
French
German
Published 14.07.2021
Subjects
BEER
BIOCHEMISTRY
CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
MUTATION OR GENETIC ENGINEERING
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
PHYSICS
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
TESTING
TRANSPORTING
VINEGAR
WINE
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Summary:The invention relates to a microfluidic system in which the droplets flow through an off-chip delay line in a linear sequential order. This ensures that all the droplets are incubated for the same amount of time and under the same conditions as they flow through the delay line. The invention further relates to the use of this microfluidic system for high throughput screening methods or in vitro evolution methods.
Bibliography:Application Number: EP20180703905