CHIMERIC ANTIGEN RECEPTOR AND NATURAL KILLER CELLS EXPRESSING SAME

The present invention relates to a chimeric antigen receptor and natural killer cells expressing the same and, more particularly, to a chimeric antigen receptor (CAR) comprising an intracellular signaling domain including all or a part of an OX40 ligand (CD252), thereby having an excellent anticance...

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Bibliographic Details
Main Authors JUNG, Mi Young, LEE, Eun Sol, HER, Jung Hyun, WON, Sung Yong, KIM, Han Sol, KIM, Hyun Ah, LIM, Ho Yong, HWANG, Yu Kyeong, CHO, Sung Yoo, GWON, Su Hyun
Format Patent
LanguageEnglish
French
German
Published 13.11.2019
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The present invention relates to a chimeric antigen receptor and natural killer cells expressing the same and, more particularly, to a chimeric antigen receptor (CAR) comprising an intracellular signaling domain including all or a part of an OX40 ligand (CD252), thereby having an excellent anticancer activity enhancing effect on immune cells, and immune cells expressing the same.
Bibliography:Application Number: EP20170886739