ALKYL SUBSTITUTED TRIAZOLE COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR

Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and may have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following stru...

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Main Authors RAMSDEN, Philip Dean, DRANSFIELD, Paul John, YEH, Wen-Chen, HOUZE, Jonathan, MA, Zhihua, DEBENEDETTO, Mikkel V, LAI, Su-Jen, HARVEY, James S, PATTAROPONG, Vatee, CHEN, Yinhong, KHAKOO, Aarif Yusuf, SHARMA, Ankit, SWAMINATH, Gayathri, NISHIMURA, Nobuko
Format Patent
LanguageEnglish
French
German
Published 25.09.2019
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Summary:Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and may have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures: (I), (II) where the definitions of the variables are provided herein.
Bibliography:Application Number: EP20170797841