ENZYMATIC PREPARATION OF PROPAMOCARB

A process for preparing Propamocarb is presented. The preparation of Propamocarb (propyl 3-(dimethylamino)propylcarbamate) from 3-dimethylaminopropylamine and dipropyl carbonate is performed using an enzyme catalyst. In certain embodiments, the catalyst is a lipase enzyme, immobilized on a solid sup...

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Bibliographic Details
Main Authors RABASSE, Jean-Michel, CLENDENNEN, Stephanie, Kay, BOAZ, Neil, Warren
Format Patent
LanguageEnglish
French
German
Published 24.06.2020
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Summary:A process for preparing Propamocarb is presented. The preparation of Propamocarb (propyl 3-(dimethylamino)propylcarbamate) from 3-dimethylaminopropylamine and dipropyl carbonate is performed using an enzyme catalyst. In certain embodiments, the catalyst is a lipase enzyme, immobilized on a solid support. Advantages of the process include the avoidance of the use of chloroformate or vinyl carbonate.
Bibliography:Application Number: EP20170791912