INHIBITION OF OLIG2 ACTIVITY

Described herein are urea compounds and pharmaceutical compositions containing such compounds, which inhibit the activity of Olig2. Also described herein are methods of using such Olig2 inhibitors, alone and in combination with other compounds, for treating cancer and other diseases. In particular t...

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Bibliographic Details
Main Authors CAMPOS, Bismarck, MCHARDY, Stanton F, LOPEZ, Ambrosio, Jr, WANG, Hua-Yu Leo, BEATON, Graham
Format Patent
LanguageEnglish
French
German
Published 03.07.2019
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Described herein are urea compounds and pharmaceutical compositions containing such compounds, which inhibit the activity of Olig2. Also described herein are methods of using such Olig2 inhibitors, alone and in combination with other compounds, for treating cancer and other diseases. In particular the Olig2 inhibitors may be used to treat glioblastoma.
Bibliography:Application Number: EP20170844525