PROCESS FOR THE PREPARATION OF AGOMELATINE IN CRYSTALLINE FORM

The present invention pertains to a process for the preparation of polymorph form X of agomelatine, which comprises providing agomelatine, and crystallizing agomelatine in the presence of at least one of an acid and a salt thereof, and to a polymorph form of agomelatine.

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Bibliographic Details
Main Authors Pavlin, Darja, Gosak, Kaja, Kidemet, Davor, Kolenc, Ivanka, Zupancic, Blaz, Benkic, Primoz
Format Patent
LanguageEnglish
French
German
Published 10.04.2019
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Summary:The present invention pertains to a process for the preparation of polymorph form X of agomelatine, which comprises providing agomelatine, and crystallizing agomelatine in the presence of at least one of an acid and a salt thereof, and to a polymorph form of agomelatine.
Bibliography:Application Number: EP20170195494