METHOD, SYSTEM AND COMPUTER PROGRAM FOR COMPUTER-ASSISTED EVALUATION OF BIOMARKERS IN A TISSUE SAMPLE

Disclosed are a method for computer-assisted evaluation of biomarkers in a tissue sample as well as a corresponding system and computer program. The method comprising the following steps: providing an image of the tissue sample in which cell nuclei of the tissue as well as biomarkers are represented...

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Bibliographic Details
Main Authors Hiemann, Rico, Elimport, Alexey, von Neubeck, Cläre
Format Patent
LanguageEnglish
French
German
Published 25.03.2020
Subjects
CALCULATING
COMPUTING
COUNTING
IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
PHYSICS
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Summary:Disclosed are a method for computer-assisted evaluation of biomarkers in a tissue sample as well as a corresponding system and computer program. The method comprising the following steps: providing an image of the tissue sample in which cell nuclei of the tissue as well as biomarkers are represented, automatically determining for a plurality of locations or regions within the image a blood vessel probability that represents a probability that the image at the corresponding location or region represents a blood vessel, automatically determining an assumed blood vessel location within said image based on a distribution of blood vessel probability with respect to said locations or regions within the image, automatically selecting biomarkers represented in said image at locations outside the assumed blood vessel location but within a threshold distance from said assumed blood vessel location, and automatically evaluating the selected biomarkers.
Bibliography:Application Number: EP20180154858