TETRAHYDROPYRAN DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN

The present invention relates to tetrahydropyran and thiopyran derivatives having dual pharmacological activity towards both the sigma (σ) receptor, and the μ-opioid receptor, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy,...

Full description

Saved in:
Bibliographic Details
Main Authors ALMANSA-ROSALES, Carmen, GARCIA-LOPEZ, Monica, RODRIGUEZ ESCRICH, Sergio, LLORENTE-FERNANDEZ, Ana Virginia, CHRISTMANN, Ute
Format Patent
LanguageEnglish
French
German
Published 27.03.2019
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:The present invention relates to tetrahydropyran and thiopyran derivatives having dual pharmacological activity towards both the sigma (σ) receptor, and the μ-opioid receptor, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy, in particular for the treatment of pain.
Bibliography:Application Number: EP20170725860