ONCOSTATIN M RECEPTOR ANTIGEN BINDING PROTEINS

The invention provides anti-oncostatin M receptor-² (OSMR) antigen binding proteins, e.g., antibodies and functional fragments, derivatives, muteins, and variants thereof. OSMR antigen binding proteins interfere with binding of OSM and/or IL-31 to OSMR. In some embodiments, anti-OSMR antigen binding...

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Bibliographic Details
Main Authors KING, Chadwick T, WEINREB, Paul H, ARNETT, Heather A, ESCOBAR, Sabine S, NARAYANAN, Saravanakumar, LIM, Ai Ching, PEDERSON, Nels E
Format Patent
LanguageEnglish
French
German
Published 20.03.2019
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:The invention provides anti-oncostatin M receptor-² (OSMR) antigen binding proteins, e.g., antibodies and functional fragments, derivatives, muteins, and variants thereof. OSMR antigen binding proteins interfere with binding of OSM and/or IL-31 to OSMR. In some embodiments, anti-OSMR antigen binding proteins are useful tools in studying diseases and disorders associated with OSMR and are particularly useful in methods of treating diseases and disorders associated with OSMR and binding of OSM and/or IL-31 to OSMR.
Bibliography:Application Number: EP20180185359